How lots of grapes remain in a bottle of white wine? A bottle of wine usually includes 25 ounces of red wine, which is equivalent to 750 mL. A basic serving of red wine is 5 ounces, which implies that each bottle contains about 5 portions. If Howtomakewinefromgrapes.com were to divide a bottle of red wine into five portions, you would end up with about 150 grapes.