Anti-Cancer Impact Of Xao Tam Phan Paramignya Trimera Methanol Root Extract On Human Breast Cancer
Xao tam phan (Paramignya trimera (Oliv.) Guillaum) can be a Vietnamese traditionally medicinal plant used in the management of numerous cancers. The preparation of Xao tam phan extracts including solvent type and extraction method have significant effects on extraction efficiency, phytochemical profile and biological activity. This study aimed to analyze the consequences of five various solvents (water, acetonitrile, methanol, ethyl acetate and hexane) and three different extraction methods (conventional, ultrasound-assisted and microwave-assisted) on phytochemical yield and antioxidant capacity of P. trimera root from Vietnam. The final results indicate that methanol extracted the maximal yield of phytochemicals from P. trimera and exhibited the maximum antioxidant capacity, with eleven compounds were identified and quantified. Microwave-assisted extraction produced the maximal phytochemical yields (aside from total flavonoids) and antioxidant capacity, when compared with conventional and ultrasound-assisted extractions. These data demonstrate that using methanol and microwave-assisted extraction are recommended for extraction of biologically active phytochemicals from P. trimera root for application inside the nutraceutical and/or pharmaceutical industries.
Drying methods, solvents and extraction methods greatly impact the phytochemical compounds and biological activity from plant materials. The aims with this study were to determine the consequences of various drying methods, various solvents and extraction methods around the phytochemical compounds and antioxidant capacity from Xao tam phan (Paramignya trimera) root from Vietnam. The final results established that microwave drying was an effective method in eliminating water regarding shortest drying time, lowest energy consumption and greatest retention of phytochemical compounds and antioxidant capacity through the P. trimera root while methanol and microwave-assisted extraction were the most effective solvent and means for greatest extraction from the phytochemical compounds and antioxidant capacity from your P. trimera root. The findings using this study allow retaining the highest numbers of phytochemical compounds and antioxidant capacity in the P. trimera root for potential application within the nutraceutical industry.
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