Anti-Cancer Effects Of Xao Tam Phan Paramignya Trimera Methanol Root Extract On Human Cancer Of The Breast

Xao tam phan (Paramignya trimera (Oliv.) Guillaum) is really a Vietnamese traditionally medicinal plant utilized in the management of numerous cancers. The preparation of Xao tam phan extracts including solvent type and extraction method have significant effects on extraction efficiency, phytochemical profile and biological activity. These studies aimed to look into the end results of five various solvents (water, acetonitrile, methanol, ethyl acetate and hexane) and three different extraction methods (conventional, ultrasound-assisted and microwave-assisted) on phytochemical yield and antioxidant capacity of P. trimera root from Vietnam. The outcome indicate that methanol extracted the maximal yield of phytochemicals from P. trimera and exhibited the best antioxidant capacity, with eleven compounds were identified and quantified. Microwave-assisted extraction produced the maximal phytochemical yields (apart from total flavonoids) and antioxidant capacity, when compared with conventional and ultrasound-assisted extractions. These data show that the use of methanol and microwave-assisted extraction are recommended for extraction of biologically active phytochemicals from P. trimera root for application within the nutraceutical and/or pharmaceutical industries.

Drying methods, solvents and extraction methods greatly get a new phytochemical compounds and biological activity from plant materials. The aims on this study could determine the effects of various drying methods, various solvents and extraction methods about the phytochemical compounds and antioxidant capacity from Xao tam phan (Paramignya trimera) root extracted from Vietnam. The final results indicated that microwave drying was a powerful method in removal of water with regards to shortest drying time, lowest energy consumption and greatest retention of phytochemical compounds and antioxidant capacity through the P. trimera root while methanol and microwave-assisted extraction were the most effective solvent and means for greatest extraction with the phytochemical compounds and antioxidant capacity from the P. trimera root. The findings from this study allow retaining the very best numbers of phytochemical compounds and antioxidant capacity through the P. trimera root for potential application in the nutraceutical industry.

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