Anti-Cancer Benefit Of Xao Tam Phan Paramignya Trimera Methanol Root Extract On Human Cancer Of The Breast

Xao tam phan (Paramignya trimera (Oliv.) Guillaum) is often a Vietnamese traditionally medicinal plant employed in the treatment of numerous cancers. The preparation of Xao tam phan extracts including solvent type and extraction method have significant effects on extraction efficiency, phytochemical profile and biological activity. These studies aimed to analyze the consequences of 5 various solvents (water, acetonitrile, methanol, ethyl acetate and hexane) and three different extraction methods (conventional, ultrasound-assisted and microwave-assisted) on phytochemical yield and antioxidant capacity of P. trimera root from Vietnam. The final results indicate that methanol extracted the maximal yield of phytochemicals from P. trimera and exhibited the highest antioxidant capacity, with eleven compounds were identified and quantified. Microwave-assisted extraction produced the maximal phytochemical yields (with the exception of total flavonoids) and antioxidant capacity, in comparison with conventional and ultrasound-assisted extractions. These data demonstrate that using methanol and microwave-assisted extraction are suggested for extraction of biologically active phytochemicals from P. trimera root for application within the nutraceutical and/or pharmaceutical industries.

Drying methods, solvents and extraction methods greatly impact the phytochemical compounds and biological activity from plant materials. The aims of the study were to determine the end results of various drying methods, various solvents and extraction methods on the phytochemical compounds and antioxidant capacity from Xao tam phan (Paramignya trimera) root extracted from Vietnam. The final results established that microwave drying was a powerful method in elimination of water regarding shortest drying time, lowest energy consumption and greatest retention of phytochemical compounds and antioxidant capacity through the P. trimera root while methanol and microwave-assisted extraction were the best solvent and way for greatest extraction in the phytochemical compounds and antioxidant capacity from your P. trimera root. The findings because of this study allow retaining the greatest amounts of phytochemical compounds and antioxidant capacity from your P. trimera root for potential application within the nutraceutical industry.

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