Anti-Cancer Influence Of Xao Tam Phan Paramignya Trimera Methanol Root Extract On Human Cancer Of The Breast
Xao tam phan (Paramignya trimera (Oliv.) Guillaum) is often a Vietnamese traditionally medicinal plant utilized in treating numerous cancers. The preparation of Xao tam phan extracts including solvent type and extraction method have significant effects on extraction efficiency, phytochemical profile and biological activity. This research aimed to investigate the consequences of 5 various solvents (water, acetonitrile, methanol, ethyl acetate and hexane) and three different extraction methods (conventional, ultrasound-assisted and microwave-assisted) on phytochemical yield and antioxidant capacity of P. trimera root from Vietnam. The outcome indicate that methanol extracted the maximal yield of phytochemicals from P. trimera and exhibited the greatest antioxidant capacity, with eleven compounds were identified and quantified. Microwave-assisted extraction produced the maximal phytochemical yields (aside from total flavonoids) and antioxidant capacity, when compared to conventional and ultrasound-assisted extractions. These data show that the usage of methanol and microwave-assisted extraction are recommended for extraction of biologically active phytochemicals from P. trimera root for application in the nutraceutical and/or pharmaceutical industries.
Drying methods, solvents and extraction methods greatly affect the phytochemical compounds and biological activity from plant materials. The aims of the study were to determine the effects of different drying methods, various solvents and extraction methods for the phytochemical compounds and antioxidant capacity from Xao tam phan (Paramignya trimera) root obtained from Vietnam. The results established that microwave drying was an effective method in removal of water regarding shortest drying time, lowest energy consumption and greatest retention of phytochemical compounds and antioxidant capacity through the P. trimera root while methanol and microwave-assisted extraction were the most effective solvent and method for greatest extraction with the phytochemical compounds and antioxidant capacity from the P. trimera root. The findings from this study allow retaining the greatest amounts of phytochemical compounds and antioxidant capacity from your P. trimera root for potential application in the nutraceutical industry.
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